New technology traces sodium blood without a single needle
In a new study, the researchers showed long -term non -invasive monitoring of sodium levels in the blood using a system that combines audio detection with teahertz spectral analysis. The precise measurement of blood sodium is necessary to diagnose and manage conditions such as dehydration, kidney disease, and some neurological disorders and endocrine.
Teahertz Badiation, which is located between microwave ovens and an infrared medium area of the electromagnetic spectrum, is ideal for biological applications because it is low energy and non -backward tissues, and it is scattered less than infrared and visible light and is sensitive to structural and functional biological changes.
“For biomedical applications, the spectral analysis of Trahezz still faces two main challenges: the discovery of molecules other than water in complex biological samples and the penetration of thick tissue layers to enable the detection inside the body,” said Zahin Tian of the University of Tianjin in China. By adding the audio audio detection, we were able to overcome these challenges and show the first in vain Discover ions using terartz waves. This is an important step towards making terartz -based technologies a process for clinical use. “
in opticalOptica Pubishing Group, the leading high -influential research, researchers describe their new multi -spectrum audio system and showed that it can be used for long -term uninterrupted monitoring of sodium concentration in living mice without the need for any stickers. The initial tests conducted with human volunteers were also promising.
“With more development, this technology can be used to monitor sodium levels in patients without the need to withdraw blood,” said Tian. “Sodium measurements can be used in an actual time to safely correct the imbalances in critical patients while avoiding serious nervous complications that can occur when sodium levels change quickly.”
Using the sound to cut noise
The new work is part of a larger project aimed at progressing and implementing Teahertz technology in the biomedical field using Teahertz Optoactic techniques. One of the main objective of the project is to reduce the interference of the water caused by water, which is strongly absorbed by terartz radiation.
To overcome this overlap, researchers have developed a normative system that displays the sample using Teahertz waves. Since the sample absorbs these waves, it vibrates sodium ions connected to the water molecules in the blood, creating ultrasound waves that are discovered using an ultrasound adapter. This technique, known as the audio audio detection, transforms the tendtz energy into an audio waves.
“The technology of Teahertz Optoacoustic is a leading progress of biomedical applications by overcoming the effective water absorption barrier, which has historically limited these applications,” said Tian. “The broader importance of this work exceeds sodium detection in the blood. This technology has the ability to determine various vital molecules – including sugars, proteins and enzymes – by identifying the signatures of the unique terartz absorption.”
Follow sodium without needles
To test their new system, the researchers have shown that it can measure the increases in sodium levels in the blood in the blood vessels under the skin of live mice on a second milliliter for more than 30 minutes. These measurements are taken from the ear, with the surface of the skin to 8 ° C to inhibit the rear audio audio signal from the water.
The researchers also showed that the TERAHERTZ Optoactic system can quickly distinguish between high and low sodium levels in human blood samples. Finally, they measured the levels of sodium ion in the blood vessels in the hands of healthy volunteers. They found that the sodium -discovered sound signal was proportional to the amount of blood flow below the surface of the skin, although the measurements were collected without any cooling of the skin. Despite the need for more work, these results indicate that the system can be beneficial for non -invasive monitoring in actual time.
The researchers say that the system’s adaptation of human use will require the determination of appropriate detection sites on the human body – such as inside the mouth – that can tolerate rapid cooling and allow strong detection a signal with minimal water background noise. They also explore the methods of treating alternative signals that may make it possible to suppress water overlap without the need for cooling, which makes the approach more practical for clinical diagnosis.
(Tagstotranslate) Kidney disease; Diseases and conditions; Pharmacy is obese; Medical devices are healthy workplace; Parkinson’s Research & amp;#039; chronic disease
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