Fasting can be twice a week as a changing games for type 2 diabetes

“This study is the first to compare the effects of three different food interventions in energy management 2 of type 2 diabetes,” said Hahao Zhang, chief doctor at the first hospital at Zengzo University, China.

Although researchers have identified the improvement of HBA1C levels, and negative events were similar in the three groups, the IER group showed greater advantages in reducing fasting glucose in the blood, improving insulin sensitivity, reducing triglycerides, and promoting commitment to food interventions.

“The research fills a gap in its comparison directly 5: 2 limitations of intermittent energy with restricted eating for 10 hours in patients with obesity and type 2 diabetes. The results provide scientific evidence for doctors to choose appropriate nutritional strategies when treating these patients,” said Zhang.

Zhang and his colleagues performed one, random experience, dominating parallel at the first affiliated Hospital of the University of Chengzhou from November 19, 2021 to November 7, 2024.

Ninety patients were randomly assigned to 1: 1: 1 to the IER, TRE or CER group, with considering weekend calories in all groups. A team of nutritionists supervised the intervention for 16 weeks.

From those registered, the completion of 63 study. There were 18 females and 45 males, with an average age of 36.8 years, which is the average duration of diabetes 1.5 years, and the basic body mass index of 31.7 kg/m², and HBA1C by 7.42 %.

At the end of the study, there were no statistically significant differences in HBA1C reduction and weight loss between IER, TRE and CER groups. However, the absolute decrease in HBA1C and body weight was greater in the IER group.

Compared to TRE and Cer, IER dramatically reduced blood glucose and triglycerides and increased Matsuda, which is a measure of completely insulin sensitivity. Euric and liver acid enzyme levels have not appeared any statistically significant changes from the foundation line in any study group.

Two patients in the IER group and the TRE group, and three patients in the CER group, have seen mild blood sugar.

The IER group got the highest compliance rate (85 %), followed by CER by 84 % and 78 % Tre group. Both IER and Cer groups showed statistically significant differences with the TRE group.

Zhang said these results highlight the feasibility and effectiveness of nutritional interventions for people with obesity and type 2 diabetes.