Drawing maps of secret escape touches for fatal brain tumors

Patients that were diagnosed with a 15 -month scrap tumor live on average.

What is required is a better way to determine those hidden cancer cells and predict a place where the tumor grows after that. Jennifer Monson believes that she and her research team at the VTC Biomedical Research Institute have developed a tool to do so.

Their way, recently described in Biomedical Innovations NPJ, It combines magnetic resonance imaging, the deeper Monson knowledge of how fluid moves through human tissue, and the Monson algorithm team is a development to determine the place where cancer may appear.

“If you cannot find cancer cells, you will not be able to kill cancer cells, be it by getting rid of them, hitting them with radiation treatment, or obtaining medicines for them,” said Monson, professor and director of the FBRI Cancer Research Center – Ronuk. “This is a way we now believe that it can allow us to find these cancer cells.”

Currently, doctors are planning surgeries to remove diet aromatic tumor tumors based on radiological surveying, but this only provides a vision of the area outside the edge of cancer. During surgery, fluorescent dyes are highlighted, but the dyes do not penetrate deeply and the cells should be visible to the eye.

“These methods will not see a cell that migrated or invaded to the tissues, and this is something we think we can do this way,” said Monson, who also holds an appointment in the Department of Biomedical Engineering and Mechanics.

Monson’s research focuses primarily on the flow of interstitial fluids – fluid movement through the distances between the cells in the tissues. The flow disposes differently in various diseases.

In the study of stoma tumor, the Monson Laboratory found that the fastest flows predict the place of invasion of cancer cells. However, a random movement is more associated with the liquid, or spread, with a lower invasion of cancer cells.

But Monson’s new scale team has proven to be the best prediction. The fluid flow around the tumor puts paths, such as the tables that merge in the rivers, which are followed by the cancer cells of migration to the surrounding tissues.

Monson said: “He can tell this surgeon as there will be a greater opportunity for more cancer cells, so they may be more aggressive, if the patient is safe to follow a more tweeting area,” Monson said.

Monson results support the work of a new rotation company, CAIRINA, which aims to improve cancer treatment through a more specialized approach to surgery and cancer treatments.

“Cairo is trying to move this to the next level,” said Monson. “Our goal is to provide surgeons and radiologists who have probable maps or hot point maps, where we expect more invasion of cancer cells to support the most aggressive therapeutic application, and also to determine where it may be a lower invasion, to help spare tissues from unnecessary treatment.”

This research was funded by grants from the National Cancer Institute, the Red Gates Foundation, the American Cancer Society, and the National Institute for Neurological Disorders and Stroke.