Colombia scientists turn yogurt into a healing gel that mimics human tissue

Posted on July 25 in topicSantiago Correa, Assistant Professor of Biomedical Engineering at Colombia Engineering, and its collaborators describe a hydrogen platform by injection that uses EVS of milk to treat long barriers in developing biomedics for renewal medicine. EVS are molecules that are naturally secreted by cells and carrying hundreds of biological signals, such as proteins and genetic substances, allowing advanced cellular communication that can not be repeated artificial materials easily.

In this study, Correa and his colleagues designed the Hydrogel system where EVS plays a dual role: it works as biologically active rats but also acts as basic building blocks, by linking biologically compatible polymers to form an injection material. Using an unconventional approach that benefits from EVS milk from yogurt, the team enables the team to overcome the restrictions of the return on the development of the biological materials based on EV. EVS enables hydrogen yogurt to simulate live tissue mechanics and involve the cells around the activity, which enhances recovery renewal and tissue renewal without the need for additional chemical additives.

“This project started as an essential issue on how to build EV. EVS gave us a practical tool for that, but it has turned into more than one model,” said Korea who led the study with Artemis Margaronis, a NSF graduate research colleague at the Correa Lab Lab. “We have found that they have a royal renewed potential, which opens the door to accessible new treatment.”

Korea directs the nanoparticles laboratory at the University of Colombia, where its research focuses on the delivery of medicines and immune engineering. He is also a member of the Herbert Erfing Center for Comprehensive Cancer and cooperated in this project with Kam Lyong, a member of the Engineering Faculty in Colombia. This study was strengthened through international cooperation with researchers from the University of Badova, including ELISA CIMETTA (Caterina Piunti. By combining the experience of the Padova team in EV agricultural sources with the experience of the Correa Laboratory in the nanopolitan and hydroma -based hydrocrites, the team showed the power of global multidisciplinary partnerships in the progress of innovation in biological materials.

Using EVS derived from yogurt, the team selects a design space to generate water gels that include EVS as structural and biological elements. They also verified the validity of the approach using the EVS derived from the cells of mammals and bacteria, which indicates that the platform is normative and is compatible with the various allegiance sources. This door can be opened to advanced applications in wound healing and regenerative medicine, as current treatments are often limited to enhancing long -term tissue repair. By integrating EVS directly into a hydrogel structure, the material allows sustainable connection to its biological active signals. Since the hydrogen may be injected, it can also be domesticated locally to the damaged tissues.

Early experiments show that ev yogurt is vital compatible and leads a strong vascular activity within one week in immune mice, indicating that agricultural EVS can only enable basic biomedics research but also carry therapeutic capabilities as vital ultimate. In mice, the article did not show any signs of a negative reaction, and instead it encouraged the formation of the new blood vessels, a major step in the regeneration of effective tissues. The Korea team also noted that hydrogen creates a unique immune environment fertilized in anti -inflammatory cells, which may contribute to the repair of the monitored tissue. The team now explores how this immune response can help direct tissue regeneration.

“Be able to design a substance that closely mimics the natural environment of the body while accelerating the healing process, it opens a new world of renewal medicine,” said Margarenis. “Such moments remind me of why the field of research in biomedical engineering is always on the threshold of something exciting.”