Common pain analgesics like Advil and Tylenol Supercharge are antibiotics resistance

In the first study of its kind, researchers found that ibuprofen and asymaminophen do not lead to antibiotic resistance only when used individually but amplify them when used together.

Evaluating the interaction between non -antibiotics drugs, a large -spectrum antibiotic, siprofloxacin, and Show the cold (E. coli) – It found common bacteria that cause gut and urinary tract infections – that ibuprofen and asytaminophen have increased significantly from bacterial mutations, making E. Coli very resistant to antibiotics.

It is important to discover serious health effects, especially for people in elderly care homes, where multiple medications are given regularly.

The World Health Organization stated that the antimicrobial resistance poses a global threat to public health, and that bacterial resistance was directly responsible for 1.27 million global deaths in 2019.

The lead researcher at the lead researcher at Unisa Rietie Veister says that the results raise important questions about the dangers of multiple medications in the care of the elderly.

Professor Professor Professor said: “Antibiotics have always been in the treatment of infectious diseases, but excessive use and abuse on a large scale pushed a global rise in antibiotic -resistant bacteria,” says Professor Professor Professor.

“This is particularly widespread in residential care facilities, where the elderly are likely to be prescribed multiple medications – not only antibiotics, but also medications for pain, sleep or blood pressure – which makes them a perfect reproductive floor to become intestinal bacteria resistant to antibiotics.

“In this study, we looked at the effect of non -advanced medications and cyberloxacin, which is an antibiotic used to treat common skin, intestine or urinary tract infections.

“When bacteria were exposed to cyberloxacin alongside ibuprofen and asymaminophen, they developed more genetic mutations than antibiotics alone, helping them to grow faster and become very resistant.

“We have also discovered the genetic mechanisms behind this resistance, as the ibuprofen and paracetamol activated bacteria defenses to expel antibiotics and make them less effective.”

The study evaluated nine commonly used drugs in the care of the elderly: ibuprofen (anti -inflammatory pain), diclofenac (anti -inflammatory to treat arthritis), acetaminophen (paracetite and patients in paracetit and fever), voroseimide (high blood pressure), and the disease -related daily. Blood fats), tramadol (stronger drug for pain surgery), Timazepam (used to treat sleep problems), and the zipper (improper).

ASSC PROF VENTER says that the study shows how antibiotic resistance is a more complex challenge than previously understood, as non -advanced common drugs also play a role.

Professor Professor Professor says: “Antibiotics resistance is no longer only related to antibiotics,” says Professor Professor Professor.

“This study is a clear reminder that we need to carefully look at the risk of using multiple-especially in caring for the elderly where the population is often prescribed a mixture of long-term treatments.

“This does not mean that we should stop using these medications, but we need to be more aware of how they interact with antibiotics-and this includes only looking beyond Duke groups.”

Researchers call for more studies on drug reactions between any person on long -term drug therapy systems so that we can get more aware of the effect of common drugs on the effectiveness of antibiotics.